Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.53 |
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819190 | 0.92 | TMPRSS2 (0.51) | TMPRSS2POLRMTPIK3CD | |
| Gs-441524 SCHEMBL22663744 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL24975226 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL15998246 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL23870459 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL24667691 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL22142944 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL22096285 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL10120691 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT | |
| Gs-441524 SCHEMBL10120689 | 0.90 | TMPRSS2 (0.60) | TMPRSS2POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4331677-A2 | METHODS OF TREATING FELINE CORONAVIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-3595672-B1 | COMPOUNDS FOR USE IN METHODS OF TREATING FELINE CORONAVIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| US-11260070-B2 | Methods of treating feline coronavirus infections | GILEAD SCIENCES, INC. (US) | 2022-03-01 | — | — | US | disclosed |
| US-20200376014-A1 | METHODS OF TREATING FELINE CORONAVIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2020-12-03 | — | — | US | disclosed |
| US-10682368-B2 | Methods of treating feline coronavirus infections | GILEAD SCIENCES, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| CN-110869028-A | Method of treating feline coronavirus infection | 吉利德科学公司 | 2020-03-06 | — | — | CN | disclosed |
| US-20180296584-A1 | METHODS OF TREATING FELINE CORONAVIRUS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11260070-B2 | Methods of treating feline coronavirus infections | SARS1, CPN1, CAT | TMPRSS2 62/4885POLRMT 36/4885PIK3CD 1772/4885 |
| US-20180296584-A1 | METHODS OF TREATING FELINE CORONAVIRUS INFECTIONS | CAT, ACE, ACE2 | TMPRSS2 11/4885POLRMT 986/4885PIK3CD 4091/4885 |
| US-10682368-B2 | Methods of treating feline coronavirus infections | SARS1, CPN1, CAT | TMPRSS2 62/4885POLRMT 36/4885PIK3CD 1772/4885 |
| US-20200376014-A1 | METHODS OF TREATING FELINE CORONAVIRUS INFECTIONS | CAT, ACE, ACE2 | TMPRSS2 9/4885POLRMT 860/4885PIK3CD 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.