Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534301 | 0.87 | ESR1 (0.43) | PRSS1CTSGCTRB1CMA1ESR1 | |
| SCHEMBL5884520 | 0.79 | SRC (0.49) | PRSS1CTSGCTRB1CMA1SRC | |
| SCHEMBL27484083 | 0.76 | KCNN4 (0.53) | PRSS1CTSGCTRB1CMA1SRC | |
| SCHEMBL29074073 | 0.76 | ESR1 (0.42) | ELANEKCNN4ESRRBESR1ESR2 | |
| SCHEMBL26966855 | 0.74 | ESR1 (0.41) | ELANEKCNN4ESRRBESR1ESR2 | |
| SCHEMBL10982127 | 0.74 | KCNN4 (0.58) | PRSS1CTSGCTRB1CMA1SRC | |
| SCHEMBL9778358 | 0.72 | CHRM2 (0.57) | SRCELANEKCNN4ESR1ESR2 | |
| SCHEMBL26966854 | 0.72 | ESR1 (0.39) | ELANEKCNN4ESRRBESR1ESR2 | |
| SCHEMBL27794813 | 0.71 | ESR1 (0.53) | ESR1ESR2ALDH1A1CYP3A4CHRM2 | |
| SCHEMBL4953286 | 0.71 | KCNN4 (0.58) | PRSS1CTSGCTRB1CMA1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590056-B2 | ERR modulators and uses thereof | CITY OF HOPE (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180297923-A1 | ERR MODULATORS AND USES THEREOF | CITY OF HOPE | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180297923-A1 | ERR MODULATORS AND USES THEREOF | ESRRA, ESRRB, ESRRG | PRSS1 4272/4885CTSG 3658/4885CTRB1 2337/4885 |
| US-10590056-B2 | ERR modulators and uses thereof | ESRRA, ESRRB, ESRRG | PRSS1 4272/4885CTSG 3658/4885CTRB1 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.