Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533747 | 0.87 | PI4KB (0.63) | PI4KBHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL20533693 | 0.86 | PI4KB (0.52) | PI4KBHPGDALDH1A1NPSR1CYP2C9 | |
| SCHEMBL20533751 | 0.85 | PI4KB (0.54) | PI4KBHPGDALDH1A1NPSR1CYP2C9 | |
| SCHEMBL20533769 | 0.85 | PI4KB (0.54) | PI4KBHPGDALDH1A1NPSR1CYP2C9 | |
| SCHEMBL20533756 | 0.85 | PI4KB (0.54) | PI4KBHPGDALDH1A1NPSR1CYP2C9 | |
| SCHEMBL20533595 | 0.85 | PI4KB (0.61) | PI4KBHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL20533551 | 0.84 | PI4KB (0.52) | PI4KBHPGDALDH1A1NPSR1HSD17B10 | |
| SCHEMBL20533903 | 0.84 | PI4KB (0.52) | PI4KBGFERJAK2JAK3PTK2 | |
| SCHEMBL20533753 | 0.84 | PI4KB (0.51) | PI4KBHPGDALDH1A1NPSR1CYP2C9 | |
| SCHEMBL20534205 | 0.83 | PI4KB (0.60) | PI4KBHPGDALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | UCB BIOPHARMA SPRL (BE) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PI4K2B, PI4KB | PI4KB 3/4885HPGD 3977/4885ALDH1A1 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.