Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429586 | 0.83 | MAPT (0.42) | CTSAPOLBLMNAMAPTKMT2A | |
| SCHEMBL21631944 | 0.81 | GAA (0.50) | CTSAPOLBSMN1; SMN2LMNAPTGFR | |
| SCHEMBL21631964 | 0.80 | CTSA (0.44) | CTSAPOLBSMN1; SMN2LMNAPTGFR | |
| SCHEMBL31446949 | 0.80 | KMT2A (0.47) | CTSAPOLBSMN1; SMN2LMNAGAA | |
| SCHEMBL20072464 | 0.79 | CYP2D6 (0.41) | SMN1; SMN2LMNAGAAKMT2AL3MBTL1 | |
| SCHEMBL17061189 | 0.78 | CTSA (0.45) | CTSAMAPTL3MBTL1 | |
| SCHEMBL9963325 | 0.76 | PLAU (0.46) | SMN1; SMN2LMNAKMT2ANPC1RAB9A | |
| SCHEMBL1207026 | 0.76 | POLB (0.57) | CTSAPOLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL30040417 | 0.76 | POLB (0.57) | CTSAPOLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11422677 | 0.75 | MAPT (0.41) | POLBLMNAMAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189011-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |