SCHEMBL20537628

SCHEMBL20537628

O=C(O)[C@@H]1C[C@H]1COc1ccc(-c2cc(OC3CCCC3)ccc2F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19321743 1.00 FFAR4 (1.00) FFAR4
SCHEMBL19307500 0.98 FFAR4 (1.00) FFAR4
SCHEMBL19307501 0.98 FFAR4 (1.00) FFAR4
SCHEMBL20032753 0.92 FFAR4 (0.84) FFAR4
SCHEMBL20032788 0.89 FFAR4 (0.84) FFAR4
SCHEMBL19307461 0.86 FFAR4 (1.00) FFAR4
SCHEMBL19307464 0.86 FFAR4 (1.00) FFAR4
SCHEMBL19307373 0.84 FFAR4 (0.81) FFAR4
SCHEMBL19307369 0.84 FFAR4 (0.81) FFAR4
SCHEMBL19307372 0.84 FFAR4 (1.00) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191454-B1 CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS BRISTOL MYERS SQUIBB CO (US) 2018-10-24 EP disclosed