SCHEMBL205377

SCHEMBL205377

CO/C=C(/C(=O)OC)c1ccccc1Oc1cccc(Oc2ncccn2)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
POLB P06746 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 3/20 0.41
HTT P42858 2/20 0.41
GAA P10253 1/20 0.41
MTNR1B P49286 1/20 0.41
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
GRM4 Q14833 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9152271 1.00 MEN1 (0.45) MEN1KMT2APOLBKDM4EMAPT
SCHEMBL29359179 1.00 MEN1 (0.45) MEN1KMT2APOLBKDM4EMAPT
SCHEMBL31289590 1.00 MEN1 (0.45) MEN1KMT2APOLBKDM4EMAPT
SCHEMBL29359688 0.90 GAA (0.39) POLBKDM4EGAAMTNR1BALDH1A1
SCHEMBL204614 0.90 GAA (0.39) POLBKDM4EGAAMTNR1BALDH1A1
SCHEMBL2857195 0.90 MEN1 (0.46) MEN1KMT2APOLBKDM4EMAPT
SCHEMBL2857201 0.90 MEN1 (0.46) MEN1KMT2APOLBKDM4EMAPT
SCHEMBL29359352 0.90 MEN1 (0.46) MEN1KMT2APOLBKDM4EMAPT
SCHEMBL29359491 0.89 KDM4E (0.52) MEN1KMT2APOLBKDM4EMTNR1B
SCHEMBL202624 0.89 KDM4E (0.52) MEN1KMT2APOLBKDM4EMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
CN-111344279-B Microbiocidal picolinamide derivatives 先正达参股股份有限公司 2023-07-07 CN disclosed
CN-108430980-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-09-02 CN disclosed
CN-109071520-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-06-14 CN disclosed
CN-111050558-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 CN disclosed
CN-111093372-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 CN disclosed
CN-108137517-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-109071522-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 CN disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 EP disclosed
EP-0690894-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AG (DE) 1996-01-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
US-5468857-A Phenylmethoxypropenoic esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-21 US disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 WO disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed
US-5334748-A A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 MEN1 420/4885KMT2A 2548/4885POLB 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.