Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19801022 | 1.00 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20538344 | 0.94 | HTT (0.59) | MEN1KMT2ASMN1; SMN2CYP1A2HDAC3 | |
| SCHEMBL20538345 | 0.94 | HTT (0.59) | MEN1KMT2ASMN1; SMN2CYP1A2HDAC3 | |
| SCHEMBL20538107 | 0.93 | BCHE (0.66) | MEN1KMT2AHDAC3TUBB4ATUBB | |
| SCHEMBL20538104 | 0.93 | BCHE (0.66) | MEN1KMT2AHDAC3TUBB4ATUBB | |
| SCHEMBL19800988 | 0.92 | TUBB1 (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20538483 | 0.92 | TUBB1 (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20538485 | 0.92 | TUBB1 (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20537896 | 0.92 | BCHE (0.58) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20538541 | 0.92 | KDM1A (0.59) | MEN1KMT2ACYP1A2HDAC3TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |