Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 3/20 | 0.75 |
| ▸ | CA9 | Q16790 | 3/20 | 0.75 |
| ▸ | CA1 | P00915 | 2/20 | 0.75 |
| ▸ | CA2 | P00918 | 2/20 | 0.75 |
| ▸ | BCHE | P06276 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KDM1A | O60341 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | STAT1 | P42224 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20537978 | 1.00 | HTT (0.82) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20537899 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20537901 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19801070 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20538153 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20538290 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20538150 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20537898 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19800968 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19801071 | 0.95 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |