SCHEMBL20538682

SCHEMBL20538682

CC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 1.00
FEN1 P39748 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15915334 1.00 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15917593 1.00 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL19272524 0.91 ALOX5AP (0.83) ALOX5APFEN1
SCHEMBL15915708 0.91 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15915727 0.91 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15915707 0.91 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15915653 0.90 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15916280 0.90 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15915651 0.90 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15916341 0.90 ALOX5AP (1.00) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2951170-B1 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2018-10-24 EP claimed