SCHEMBL20538701

SCHEMBL20538701

CC(O)CNS(=O)(=O)c1ccccc1-c1cnc(-c2cnc(N)nc2)c(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 20/20 1.00
ALOX5AP P20292 14/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15936661 1.00 FEN1 (1.00) FEN1ALOX5AP
SCHEMBL15915757 1.00 FEN1 (1.00) FEN1ALOX5AP
SCHEMBL17367735 0.92 FEN1 (0.85) FEN1ALOX5AP
SCHEMBL20538666 0.89 FEN1 (1.00) FEN1ALOX5AP
SCHEMBL15916635 0.89 FEN1 (1.00) FEN1ALOX5AP
SCHEMBL15932361 0.89 FEN1 (1.00) FEN1ALOX5AP
SCHEMBL21089363 0.85 FEN1 (0.81) FEN1ALOX5AP
SCHEMBL15936668 0.85 FEN1 (1.00) FEN1ALOX5AP
SCHEMBL17085029 0.84 FEN1 (0.83) FEN1ALOX5AP
SCHEMBL15936678 0.84 FEN1 (1.00) FEN1ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2951170-B1 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2018-10-24 EP claimed