Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054199 | 1.00 | EIF2AK4 (0.54) | EIF2AK4 | |
| SCHEMBL2054196 | 0.85 | EIF2AK4 (0.42) | EIF2AK4 | |
| SCHEMBL2036807 | 0.81 | EIF2AK4 (0.47) | EIF2AK4 | |
| SCHEMBL1992515 | 0.81 | EIF2AK4 (0.51) | EIF2AK4 | |
| SCHEMBL12614643 | 0.81 | EIF2AK4 (0.47) | EIF2AK4 | |
| SCHEMBL1992517 | 0.81 | EIF2AK4 (0.51) | EIF2AK4 | |
| SCHEMBL2040117 | 0.80 | EIF2AK4 (0.47) | EIF2AK4 | |
| SCHEMBL2040116 | 0.80 | EIF2AK4 (0.47) | EIF2AK4 | |
| SCHEMBL1997654 | 0.80 | EIF2AK4 (0.50) | EIF2AK4 | |
| SCHEMBL2000295 | 0.80 | EIF2AK4 (0.47) | EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516436-A1 | IMIDAZOPYRIDINE DERIVATIVES AS JAK INHIBITORS | Almirall S.A. (ES) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076419-A1 | IMIDAZOPYRIDINE DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |