Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 20/20 | 0.76 |
| ▸ | BPTF | Q12830 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17916722 | 1.00 | KAT2B (0.76) | KAT2BBPTF | |
| SCHEMBL17916727 | 0.86 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17916723 | 0.85 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17912347 | 0.81 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17912400 | 0.81 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17912345 | 0.81 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17912350 | 0.80 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17912366 | 0.79 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17912368 | 0.79 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL17916701 | 0.79 | KAT2B (1.00) | KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3242874-B1 | PYRIDAZINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | GENENTECH INC (US) | 2018-10-31 | — | — | EP | disclosed |