Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.63 |
| ▸ | CCR1 | P32246 | 5/20 | 0.41 |
| ▸ | DDT | P30046 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023287 | 0.93 | ELANE (0.65) | ELANECCR1 | |
| SCHEMBL17023263 | 0.87 | ELANE (0.62) | ELANECCR1 | |
| SCHEMBL17023259 | 0.87 | ELANE (0.62) | ELANECCR1 | |
| SCHEMBL17035601 | 0.87 | ELANE (0.62) | ELANECCR1 | |
| SCHEMBL17035600 | 0.87 | ELANE (0.62) | ELANECCR1 | |
| SCHEMBL17023258 | 0.87 | ELANE (0.62) | ELANECCR1 | |
| SCHEMBL17023264 | 0.87 | ELANE (0.62) | ELANECCR1 | |
| SCHEMBL17023275 | 0.87 | ELANE (0.73) | ELANECCR1 | |
| SCHEMBL17023272 | 0.86 | ELANE (0.66) | ELANECCR1DDT | |
| SCHEMBL17023278 | 0.86 | ELANE (0.74) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107911-B1 | SUBSTITUTED PYRIDONES AND PYRAZINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2018-10-31 | — | — | EP | disclosed |