Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4244380 | 0.92 | PARP1 (0.49) | PARP1 | |
| SCHEMBL8050461 | 0.85 | PARP1 (0.74) | PARP1 | |
| SCHEMBL2208157 | 0.85 | PARP1 (0.74) | PARP1 | |
| SCHEMBL8242343 | 0.85 | PARP1 (0.67) | PARP1 | |
| SCHEMBL1806111 | 0.85 | PARP1 (0.67) | PARP1 | |
| SCHEMBL8055652 | 0.85 | PARP1 (0.74) | PARP1 | |
| SCHEMBL5131450 | 0.81 | PARP1 (0.79) | PARP1 | |
| SCHEMBL1804463 | 0.73 | PARP1 (0.47) | PARP1 | |
| SCHEMBL3076203 | 0.71 | PARP1 (0.67) | PARP1 | |
| SCHEMBL3068304 | 0.71 | PARP1 (0.49) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029551-B1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MSD ITALIA SRL (IT) | 2018-10-31 | — | — | EP | claimed |