Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3911407 | 0.96 | PARP1 (0.71) | PARP1 | |
| SCHEMBL20544626 | 0.87 | PARP1 (0.91) | PARP1 | |
| SCHEMBL20544558 | 0.87 | PARP1 (1.00) | PARP1 | |
| SCHEMBL20544245 | 0.85 | PARP1 (1.00) | PARP1 | |
| SCHEMBL20544674 | 0.85 | PARP1 (1.00) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3919428 | 0.84 | PARP1 (0.83) | PARP1 | |
| SCHEMBL17160852 | 0.84 | PARP1 (0.78) | PARP1 | |
| SCHEMBL20544503 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL20544637 | 0.83 | PARP1 (0.81) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3921139 | 0.83 | PARP1 (0.92) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029551-B1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MSD ITALIA SRL (IT) | 2018-10-31 | — | — | EP | claimed |