Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128476 | 0.76 | TAAR1 (0.52) | MAOBSLC6A2SLC6A3TAAR1 | |
| SCHEMBL2470972 | 0.74 | TAAR1 (0.50) | KDM1ARCOR1MAOAMAOBTAAR1 | |
| SCHEMBL2298160 | 0.72 | TDP1 (0.39) | KDM1ARCOR1KCNH2KDM1BPARP1 | |
| SCHEMBL29331986 | 0.72 | IGF1R (0.40) | KDM1AKCNH2KDM1BPARP1 | |
| SCHEMBL29410058 | 0.72 | TDP1 (0.39) | KDM1ARCOR1KCNH2KDM1BPARP1 | |
| SCHEMBL14555727 | 0.72 | IGF1R (0.40) | KDM1AKCNH2KDM1BPARP1 | |
| SCHEMBL8619701 | 0.71 | CNR1 (0.44) | KDM1ARCOR1KCNH2KDM1B | |
| SCHEMBL8084327 | 0.71 | KDM1A (0.35) | KDM1ARCOR1KCNH2KDM1BPARP1 | |
| SCHEMBL2302020 | 0.71 | KDM4E (0.47) | KDM1AKCNH2KDM1BPARP1 | |
| SCHEMBL29410056 | 0.71 | KDM4E (0.47) | KDM1AKCNH2KDM1BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018197583-A1 | USE OF A COMBINATIONAL THERAPY OF LSD1 INHIBITORS WITH P21 ACTIVATORS IN THE TREATMENT OF CANCER | ISTITUTO EUROPEO DI ONCOLOGIA (IT) | 2018-11-01 | — | — | WO | disclosed |