SCHEMBL20547710

CO[C@@H]1[C@@H]2OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](OP(=O)(S)OC[C@H]2O[C@H]1n1cnc2c(=O)n4cc[nH]c4nc21)[C@@H]3O

nearest known ligand 0.59

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	STING1	Q86WV6	20/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25808076	0.90	STING1 (0.69)	STING1
SCHEMBL20548081	0.90	STING1 (0.69)	STING1
SCHEMBL23610241	0.90	STING1 (0.69)	STING1
SCHEMBL30473305	0.90	STING1 (0.69)	STING1
SCHEMBL20548247	0.89	STING1 (0.65)	STING1
SCHEMBL20547864	0.89	STING1 (0.68)	STING1
SCHEMBL20548164	0.86	STING1 (0.69)	STING1
SCHEMBL20548018	0.85	STING1 (0.73)	STING1
SCHEMBL20547753	0.85	STING1 (0.60)	STING1
SCHEMBL21356534	0.83	STING1 (0.69)	STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018198084-A1	CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES	LUPIN LIMITED (IN)	2018-11-01	—	—	WO	claimed