⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16657572 | 1.00 | — | — | |
| SCHEMBL2174072 | 1.00 | — | — | |
| SCHEMBL12602390 | 0.97 | CA1 (0.65) | — | |
| SCHEMBL12602391 | 0.80 | CA1 (0.48) | — | |
| SCHEMBL13057193 | 0.80 | — | — | |
| SCHEMBL10811426 | 0.80 | CA1 (0.54) | — | |
| SCHEMBL22171228 | 0.80 | — | — | |
| SCHEMBL5918105 | 0.80 | CA1 (0.48) | — | |
| SCHEMBL11124096 | 0.80 | CA1 (0.42) | — | |
| SCHEMBL2343477 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615534-A1 | FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018197503-A1 | FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2018-11-01 | — | — | WO | disclosed |