Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548018 | 0.94 | STING1 (0.73) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL20548164 | 0.93 | STING1 (0.69) | STING1 | |
| SCHEMBL20547864 | 0.90 | STING1 (0.68) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL20548247 | 0.87 | STING1 (0.65) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL23477343 | 0.85 | STING1 (1.00) | STING1 | |
| SCHEMBL29881479 | 0.85 | STING1 (1.00) | STING1 | |
| SCHEMBL18510622 | 0.85 | STING1 (1.00) | STING1 | |
| SCHEMBL18490536 | 0.85 | STING1 (1.00) | STING1 | |
| SCHEMBL30849559 | 0.85 | STING1 (1.00) | STING1 | |
| SCHEMBL20548081 | 0.85 | STING1 (0.69) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | claimed |