SCHEMBL20547951

CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[PH](=O)O)[C@@H](COP(=S)(OCCC#N)O[C@@H]2[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@H]2n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@H]1n1cnc2c(=O)n3cc[nH]c3nc21

nearest known ligand 0.36

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY12	Q9H244	11/20	0.35

▸	PRMT6	Q96LA8	1/20	0.34

▸	ADORA1	P30542	2/20	0.33

▸	DNPH1	O43598	2/20	0.33

▸	P2RY2	P41231	1/20	0.33

▸	P2RY1	P47900	1/20	0.33

▸	P2RY6	Q15077	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20548026	0.94	P2RY12 (0.35)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL20547915	0.93	P2RY12 (0.36)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL20547957	0.92	P2RY12 (0.33)	P2RY12PRMT6ADORA1P2RY2P2RY1
SCHEMBL17860495	0.88	P2RY12 (0.38)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL20022045	0.88	P2RY12 (0.37)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL18917301	0.87	P2RY12 (0.39)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL18927171	0.87	P2RY12 (0.39)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL20214158	0.86	P2RY12 (0.35)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL21137642	0.86	P2RY12 (0.35)	P2RY12PRMT6ADORA1DNPH1P2RY2
SCHEMBL22301424	0.86	KDM4E (0.39)	P2RY12PRMT6ADORA1DNPH1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018198084-A1	CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES	LUPIN LIMITED (IN)	2018-11-01	—	—	WO	disclosed