Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 12/20 | 0.89 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.89 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.89 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.89 |
| ▸ | FECH | P22830 | 1/20 | 0.89 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.89 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.89 |
| ▸ | CLK1 | P49759 | 1/20 | 0.89 |
| ▸ | GSK3A | P49840 | 1/20 | 0.89 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.89 |
| ▸ | MELK | Q14680 | 1/20 | 0.89 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.89 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.89 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.89 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.89 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.82 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.82 |
| ▸ | RIOK2 | Q9BVS4 | 8/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ATR | Q13535 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bgt-226 Free Base SCHEMBL146939 | 0.94 | MTOR (1.00) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL29388241 | 0.94 | MTOR (1.00) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL29388607 | 0.94 | MTOR (1.00) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL29351405 | 0.94 | MTOR (1.00) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL29394351 | 0.89 | MTOR (0.89) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL996047 | 0.89 | MTOR (0.89) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL31326455 | 0.89 | MTOR (0.89) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| Bgt-226 Free Base SCHEMBL996046 | 0.89 | MTOR (0.89) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL24455231 | 0.88 | MTOR (0.89) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL928275 | 0.86 | MTOR (0.86) | MTORPIK3CAPIK3CDCSNK2A2FECH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615548-A1 | BIS 2'-5'-RR-(3'F-A)(3'F-A) CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF | Aduro Biotech, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018198076-A1 | BIS 2'-5'-RR-(3'F-A)(3'F-A) CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF | Aduro Biotech, Inc. (US) | 2018-11-01 | — | — | WO | disclosed |