Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.80 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.80 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.64 |
| ▸ | IL1B | P01584 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15559912 | 0.90 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL22827076 | 0.90 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL16569284 | 0.90 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18546682 | 0.90 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2384927 | 0.89 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29569032 | 0.89 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL20792015 | 0.88 | DDB1 (0.76) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29794467 | 0.88 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2382531 | 0.88 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL3786734 | 0.88 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3622960-A1 | NATURAL KILLER CELLS FROM PLACENTA | Celularity, Inc. (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3489352-A1 | TUMOR SUPPRESSION USING HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER CELLS AND IMMUNOMODULATORY COMPOUNDS | Celularity, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |
| EP-2411506-B1 | TUMOR SUPPRESSION USING HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER CELLS AND IMMUNOMODULATORY COMPOUNDS | CELULARITY INC (US) | 2018-11-07 | — | — | EP | disclosed |