SCHEMBL20548752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL35210318	1.00	EGFR (0.59)	EGFRERBB3IGF1RKCNH2ALK
	SCHEMBL19089564	0.94	EGFR (0.59)	EGFRALKEML4
	SCHEMBL20655511	0.93	EGFR (0.60)	EGFRALKEML4
	SCHEMBL19089340	0.91	EGFR (0.51)	EGFRERBB3IGF1RKCNH2
	SCHEMBL35210287	0.90	EGFR (0.58)	EGFRALKEML4
	SCHEMBL20548847	0.90	EGFR (0.58)	EGFRALKEML4
	SCHEMBL20548919	0.89	EGFR (0.58)	EGFRERBB3ALKEML4
	SCHEMBL35210335	0.89	EGFR (0.58)	EGFRERBB3ALKEML4
	SCHEMBL20548864	0.89	EGFR (0.58)	EGFRALKEML4
	SCHEMBL35210291	0.89	EGFR (0.58)	EGFRALKEML4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.