Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DDX3X | O00571 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749259 | 0.91 | ABCG2 (0.44) | ABCG2ABCB1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20552634 | 0.89 | ABCG2 (0.42) | ABCG2ABCB1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20551944 | 0.89 | ABCG2 (0.42) | ABCG2ABCB1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20551705 | 0.88 | ABCG2 (0.42) | ABCG2ABCB1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20552570 | 0.88 | ABCG2 (0.42) | ABCG2ABCB1LMNAALDH1A1RAB9A | |
| SCHEMBL20551679 | 0.88 | ABCG2 (0.45) | ABCG2ABCB1ALDH1A1MAPT | |
| SCHEMBL20552316 | 0.87 | ABCG2 (0.39) | ABCG2ABCB1LMNAALDH1A1RAB9A | |
| SCHEMBL20553252 | 0.86 | ABCG2 (0.41) | ABCG2ABCB1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20552781 | 0.86 | ABCG2 (0.41) | ABCG2ABCB1LMNAALDH1A1RAB9A | |
| SCHEMBL20552399 | 0.85 | ABCG2 (0.42) | ABCG2ABCB1LMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618818-A1 | NON-FUSED TRICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2020-03-11 | — | — | EP | disclosed |
| WO-2018204532-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2018-11-08 | — | — | WO | disclosed |