Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670170 | 1.00 | ADORA1 (0.51) | ADORA1ESR2NR1H2MEN1KMT2A | |
| SCHEMBL21496681 | 0.90 | DDB1 (0.48) | ADORA1ESR2MEN1KMT2AMAPK1 | |
| SCHEMBL19739032 | 0.87 | ESR2 (0.51) | ESR2NR1H2TMEM97SIGMAR1MAPK1 | |
| SCHEMBL1570606 | 0.86 | ESR2 (0.54) | ADORA1ESR2NR1H2TMEM97SIGMAR1 | |
| SCHEMBL29801280 | 0.86 | ESR2 (0.54) | ADORA1ESR2NR1H2TMEM97SIGMAR1 | |
| SCHEMBL14895889 | 0.84 | ESR2 (0.53) | ESR2NR1H2TMEM97SIGMAR1MAPK1 | |
| SCHEMBL24628746 | 0.83 | ESR2 (0.56) | ADORA1ESR2NR1H2MEN1KMT2A | |
| SCHEMBL19608875 | 0.83 | ESR2 (0.56) | ESR2NR1H2TMEM97SIGMAR1MAPK1 | |
| SCHEMBL25107642 | 0.82 | ESR2 (0.51) | ADORA1ESR2NR1H2TMEM97SIGMAR1 | |
| SCHEMBL14868188 | 0.81 | ESR2 (0.50) | ESR2NR1H2TMEM97SIGMAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| WO-2018205948-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-11-15 | — | — | WO | disclosed |