Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20559758 | 1.00 | IDH1 (0.55) | IDH1 | |
| SCHEMBL20559477 | 0.92 | IDH1 (0.54) | IDH1 | |
| SCHEMBL17603341 | 0.92 | IDH1 (0.54) | IDH1 | |
| SCHEMBL17603322 | 0.90 | IDH1 (0.53) | IDH1 | |
| SCHEMBL20560029 | 0.86 | IDH1 (0.56) | IDH1 | |
| SCHEMBL20560028 | 0.86 | IDH1 (0.56) | IDH1 | |
| SCHEMBL20560272 | 0.85 | IDH1 (0.63) | IDH1 | |
| SCHEMBL20559858 | 0.85 | IDH1 (0.50) | IDH1 | |
| SCHEMBL20560269 | 0.85 | IDH1 (0.63) | IDH1 | |
| SCHEMBL20559955 | 0.85 | IDH1 (0.50) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194375-B1 | PHENYL QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA THERAPEUTICS INC (US) | 2018-11-21 | — | — | EP | claimed |