Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.67 |
| ▸ | F2 | P00734 | 8/20 | 0.65 |
| ▸ | PLAU | P00749 | 4/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.55 |
| ▸ | HPN | P05981 | 1/20 | 0.55 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328969 | 1.00 | F10 (0.67) | F10F2PLAUST14HPN | |
| Hydrochloric Acid SCHEMBL1329733 | 0.99 | F10 (0.66) | F10F2PLAUST14HPN | |
| SCHEMBL1328461 | 0.90 | PLG (0.57) | F10PLAUST14HPNHGFAC | |
| SCHEMBL20560096 | 0.90 | PLG (0.57) | F10PLAUST14HPNHGFAC | |
| SCHEMBL10309164 | 0.89 | PLAU (0.69) | F10F2PLAUST14PLG | |
| SCHEMBL29692600 | 0.89 | PLAU (0.69) | F10F2PLAUST14PLG | |
| SCHEMBL20560510 | 0.89 | PLAU (0.69) | F10F2PLAUST14PLG | |
| Hydrochloric Acid SCHEMBL29808155 | 0.88 | PLAU (0.68) | F10F2PLAUST14PLG | |
| SCHEMBL1460406 | 0.87 | F2 (0.56) | F10F2PLAUST14HPN | |
| SCHEMBL18594808 | 0.86 | F2 (0.54) | F10F2PLAUST14HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349241-B1 | PHARMACEUTICAL COMPOSITIONS WITH ATTENUATED RELEASE OF PHENOLIC OPIOIDS | SIGNATURE THERAPEUTICS INC (US) | 2019-06-19 | — | — | EP | claimed |
| EP-2560486-B1 | COMPOSITIONS COMPRISING ENZYME-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF | SIGNATURE THERAPEUTICS INC (US) | 2018-11-21 | — | — | EP | claimed |