⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13686459 | 0.96 | — | — | |
| SCHEMBL10343755 | 0.96 | — | — | |
| SCHEMBL882628 | 0.96 | TSHR (0.33) | — | |
| SCHEMBL19058816 | 0.96 | — | — | |
| SCHEMBL18636888 | 0.96 | TSHR (0.33) | — | |
| SCHEMBL2759957 | 0.87 | — | — | |
| SCHEMBL7928290 | 0.76 | — | — | |
| SCHEMBL8484 | 0.76 | — | — | |
| SCHEMBL687165 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL129069 | 0.71 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040518-A1 | BIORESORBABLE, STEREOCHEMICALLY DEFINED ELASTOMERS AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2022-02-24 | — | — | WO | disclosed |
| EP-2225261-B1 | BOROPEPTIDE INHIBITORS OF ENTEROPEPTIDASE AND THEIR USES IN TREATMENT OF OBESITY, OVERWEIGHT AND/OR DISEASES ASSOCIATED WITH AN ABNORMAL FAT METABOLISM | OBE THERAPY BIOTECHNOLOGY (FR) | 2016-03-09 | — | — | EP | disclosed |
| EP-2086953-B1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, PHASE DIFFERENCE FILM AND LIQUID CRYSTAL DISPLAY USING THE SAME | FUJIFILM CORP (JP) | 2013-03-20 | — | — | EP | disclosed |
| WO-2012097013-A1 | IRAK INHIBITORS AND USES THEREOF | NIMBUS IRIS, INC. (US) | 2012-07-19 | — | — | WO | disclosed |
| US-8188076-B2 | Compositions, synthesis, and methods of utilizing arylpiperazine derivatives | REVIVA PHARMACEUTICALS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| EP-1990339-B1 | DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM AND LIQUID CRYSTAL DISPLAY UNIT | NIPPON OIL CORP (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8163956-B2 | Inhibitors of GLYT1 transporters | MERCK SHARP & DOHME CORP. (US) | 2012-04-24 | — | — | US | disclosed |
| EP-2006351-B1 | LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM | NIPPON OIL CORP (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110124820-A1 | SUPRAMOLECULAR STRUCTURE OF HAVING SUB-NANO SCALE ORDERING | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KP) | 2011-05-26 | — | — | US | disclosed |
| US-20100216783-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF UTILIZING ARYLPIPERAZINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. | 2010-08-26 | — | — | US | disclosed |
| WO-2010034026-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20090286765-A1 | Therapeutic Agents | MERCK SHARP & DOHME (UK) LIMITED (GB) | 2009-11-19 | — | — | US | disclosed |
| US-7601714-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| WO-2009099677-A2 | THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| EP-1866286-B1 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF PKC-THETA | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008076904-A1 | BIS-SULFHYDRYL MACROCYCLIZATION SYSTEMS | AILERON THERAPEUTICS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| EP-1803773-A1 | POLYMERIZABLE LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL FILM MADE FROM THE COMPOSITION | Nippon Oil Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |