Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.71 |
| ▸ | PGGT1B | P53609 | 14/20 | 0.71 |
| ▸ | FNTB | P49356 | 13/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1396830 | 1.00 | FNTA (0.71) | FNTAPGGT1BFNTBTDP1BCL2L1 | |
| Trifluoroacetic Acid SCHEMBL31561401 | 1.00 | FNTA (0.71) | FNTAPGGT1BFNTBTDP1BCL2L1 | |
| Trifluoroacetic Acid SCHEMBL21933140 | 1.00 | FNTA (0.71) | FNTAPGGT1BFNTBTDP1BCL2L1 | |
| SCHEMBL4280385 | 0.95 | FNTA (0.78) | FNTAPGGT1BFNTBTDP1BCL2L1 | |
| SCHEMBL20564402 | 0.90 | FNTA (0.61) | FNTAPGGT1BFNTBTDP1BCL2L1 | |
| SCHEMBL10018886 | 0.88 | FNTA (0.66) | FNTAPGGT1BFNTBTDP1 | |
| Trifluoroacetic Acid SCHEMBL16112378 | 0.85 | FNTA (0.91) | FNTAPGGT1BFNTBTDP1BCL2L1 | |
| SCHEMBL7608404 | 0.85 | FNTA (0.71) | FNTAPGGT1BFNTB | |
| SCHEMBL16136628 | 0.85 | FNTA (0.71) | FNTAPGGT1BFNTB | |
| SCHEMBL6775184 | 0.85 | FNTA (0.69) | FNTAPGGT1BFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200147047-A1 | Methods of Treating Resistant Cancers | UNIVERSITY OF BALTIMORE, MARYLAND (US) | 2020-05-14 | — | — | US | claimed |
| WO-2018213748-A1 | METHODS OF TREATING RESISTANT CANCERS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-11-22 | — | — | WO | claimed |
| WO-2018213748-A1 | METHODS OF TREATING RESISTANT CANCERS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-11-22 | — | — | WO | disclosed |