Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 19/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 19/20 | 0.77 |
| ▸ | CHRM3 | P20309 | 19/20 | 0.77 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.73 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17317400 | 0.90 | CHRM2 (0.72) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL20565725 | 0.89 | CHRM2 (0.64) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL19856658 | 0.89 | CHRM2 (0.85) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL2831962 | 0.87 | CHRM1 (1.00) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL2832235 | 0.84 | CHRM2 (1.00) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL2834759 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL19856560 | 0.82 | CHRM2 (0.68) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL19856635 | 0.82 | CHRM3 (0.73) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL19856624 | 0.82 | CHRM3 (0.80) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL2832570 | 0.81 | CHRM2 (0.75) | CHRM2CHRM1CHRM3CHRM5CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152202-B1 | 3,5-DICHLORO,4-(3,4-(CYCLO-)ALKOXYPHENYL)--2-CARBONYLOXY)ETHYL)PYRIDINE DERIVATIVES AS PDE-4 INHIBITORS AND MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-11-28 | — | — | EP | claimed |
| EP-3152202-B1 | 3,5-DICHLORO,4-(3,4-(CYCLO-)ALKOXYPHENYL)--2-CARBONYLOXY)ETHYL)PYRIDINE DERIVATIVES AS PDE-4 INHIBITORS AND MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-11-28 | — | — | EP | disclosed |