SCHEMBL20565698

SCHEMBL20565698

O=CCCCOC(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
TSHR P16473 2/20 0.36
MAPT P10636 1/20 0.31
FAAH O00519 2/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14312565 0.91 TSHR (0.41) HIF1ATSHRFAAHTRPV1
SCHEMBL4188627 0.75
SCHEMBL3335979 0.75 TSHR (0.36) TSHR
SCHEMBL9626017 0.75 HIF1A (0.43) HIF1ATSHRMAPTFAAHTRPV1
SCHEMBL1608194 0.74
SCHEMBL17295373 0.74
SCHEMBL2557837 0.71 HIF1A (0.39) HIF1ATSHR
SCHEMBL14992268 0.70
SCHEMBL17367968 0.70
SCHEMBL10949134 0.70 TSHR (0.42) HIF1ATSHRMAPTFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3635022-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME Etna-Tec, Ltd (US) 2020-04-15 EP disclosed
WO-2018213850-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA-TEC, LTD (US) 2018-11-22 WO disclosed