SCHEMBL20567404

SCHEMBL20567404

C=C(C)C(=O)OCCC[Si](OC)(OC)OC.C=C[Si](OC)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
THRB P10828 1/20 0.39
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8981529 0.90 TSHR (0.42) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28057389 0.90 TSHR (0.38) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1013984 0.90 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL28052131 0.89 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28274622 0.89 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5446210 0.89 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15276 0.89 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6216027 0.89 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19411012 0.89 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4437900 0.89 TSHR (0.37) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10576307-B2 Hair-treatment compositions, methods, and kits for treating hair L'OREAL (FR) 2020-03-03 US disclosed
US-10561599-B2 Methods and kits for treating chemically relaxed hair L'OREAL (FR) 2020-02-18 US disclosed
CN-110511593-A Azo pigments, colored filter and colorant and coloured composition and display device and photographing element comprising it for it TOYO INK SC HOLDINGS CO LTD 2019-11-29 CN disclosed
CN-109960108-A Colored filter coloured composition and colored filter 东洋油墨SC控股株式会社 2019-07-02 CN disclosed
CN-106574999-B Colored resin composition for color filter, and display device DNP精细化工股份有限公司 2019-03-22 CN disclosed
WO-2018218007-A1 METHODS AND KITS FOR TREATING CHEMICALLY RELAXED HAIR L'OREAL (FR) 2018-11-29 WO disclosed
WO-2018218009-A2 HAIR-TREATMENT COMPOSITIONS, METHODS, AND KITS FOR TREATNG HAIR L'OREAL (FR) 2018-11-29 WO disclosed
US-20180339175-A1 HAIR-TREATMENT COMPOSITIONS, METHODS, AND KITS FOR TREATING HAIR L'OREAL (FR) 2018-11-29 US disclosed
US-20180338901-A1 METHODS AND KITS FOR TREATING CHEMICALLY RELAXED HAIR L'OREAL (FR) 2018-11-29 US disclosed
CN-104238267-B Color composition for color filter and colour filter 东洋油墨SC控股株式会社 2018-11-06 CN disclosed
CN-108474885-A Solid-state imager near infrared ray absorbing composition and filter 东洋油墨SC控股株式会社 2018-08-31 CN disclosed
CN-106574999-A Colored resin composition for color filter, and display device DNP精细化工股份有限公司 2017-04-19 CN disclosed
CN-1244004-C Organic-inorganic composition granule and production method thereof NIPPON CATALYTIC CHEM IND (JP) 2006-03-01 CN disclosed
CN-1423154-A Organic-inorganic composition granule and production method thereof NIPPON CATALYTIC CHEM IND (JP) 2003-06-11 CN disclosed
CN-1109707-C Organic-inorganic composite particles and method for producing same NIPPON CATALYTIC CHEM IND (JP) 2003-05-28 CN disclosed
CN-1107234-A Organic-inorganic composite particles and method for producing same NIPPON CATALYTIC CHEM IND (JP) 1995-08-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10576307-B2 Hair-treatment compositions, methods, and kits for treating hair OTC, TET3, SUCLG1 TSHR 1885/4885THRB 995/4885POLB 396/4885
US-10561599-B2 Methods and kits for treating chemically relaxed hair CRAT, DNMT1, TET3 TSHR 852/4885THRB 591/4885POLB 601/4885
US-20180339175-A1 HAIR-TREATMENT COMPOSITIONS, METHODS, AND KITS FOR TREATING HAIR OTC, TET3, SUCLG1 TSHR 1885/4885THRB 995/4885POLB 396/4885
US-20180338901-A1 METHODS AND KITS FOR TREATING CHEMICALLY RELAXED HAIR CRAT, DNMT1, TET3 TSHR 852/4885THRB 591/4885POLB 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.