Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 15/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907451 | 0.79 | PNP (0.55) | PNP | |
| SCHEMBL13691975 | 0.75 | PNP (0.62) | PNP | |
| SCHEMBL6643757 | 0.70 | PNP (0.56) | PNP | |
| SCHEMBL15628196 | 0.70 | PDPK1 (0.55) | PNP | |
| SCHEMBL1946264 | 0.69 | PNP (1.00) | PNP | |
| SCHEMBL1945120 | 0.69 | PNP (1.00) | PNP | |
| SCHEMBL1945118 | 0.69 | PNP (1.00) | PNP | |
| Hydrochloric Acid SCHEMBL1946553 | 0.68 | PNP (0.97) | PNP | |
| Hydrochloric Acid SCHEMBL1946550 | 0.68 | PNP (0.97) | PNP | |
| SCHEMBL4736800 | 0.68 | PNP (0.50) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630769-A1 | NOVEL DUAL MODE OF ACTION SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | Topadur Pharma AG (CH) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215433-A1 | NOVEL DUAL MODE OF ACTION SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | TOPADUR PHARMA AG (CH) | 2018-11-29 | — | — | WO | disclosed |