Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209262 | 0.74 | KMT2A (0.47) | BCHEMEN1KMT2AHTTGABRA1 | |
| SCHEMBL20569871 | 0.73 | BCHE (0.39) | BCHEMEN1KMT2AP2RX4HTT | |
| SCHEMBL1127344 | 0.70 | MEN1 (0.42) | BCHEMEN1KMT2AHTTLPO | |
| Biphenyl SCHEMBL3255863 | 0.61 | TSHR (0.54) | KMT2ARAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9791225 | 0.61 | KMT2A (0.60) | MEN1KMT2AHTTRAB9AMAPT | |
| SCHEMBL8076273 | 0.61 | KMT2A (0.67) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL10959666 | 0.61 | GRM5 (0.57) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| Biphenyl SCHEMBL27677322 | 0.60 | TSHR (0.52) | KMT2ARAB9AMAPTALDH1A1SMN1; SMN2 | |
| Biphenyl SCHEMBL27819830 | 0.60 | SMN1; SMN2 (0.56) | KMT2ARAB9AMAPTALDH1A1SMN1; SMN2 | |
| Biphenyl SCHEMBL27492413 | 0.60 | TSHR (0.52) | KMT2ARAB9AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630728-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | Oxford University Innovation Limited (GB) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215799-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2018-11-29 | — | — | WO | disclosed |