SCHEMBL20568793

SCHEMBL20568793

Cn1c(=O)n(CCS(C)(=O)=O)c2cc(Nc3ccnc(Cl)c3C#N)ccc21

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357285 1.00 BCL6 (0.77) BCL6
SCHEMBL23388959 0.87 BCL6 (1.00) BCL6
SCHEMBL20569756 0.85 BCL6 (1.00) BCL6
SCHEMBL20569510 0.85 BCL6 (1.00) BCL6
SCHEMBL20569509 0.85 BCL6 (1.00) BCL6
SCHEMBL30745326 0.85 BCL6 (1.00) BCL6
SCHEMBL29960423 0.85 BCL6 (1.00) BCL6
SCHEMBL29960164 0.85 BCL6 (1.00) BCL6
SCHEMBL20569639 0.84 BCL6 (1.00) BCL6
SCHEMBL20570290 0.84 BCL6 (0.76) BCL6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12110286-B2 Benzimidazolone derived inhibitors of BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-10-08 — — US claimed
EP-3630291-B9 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-05-29 — — EP claimed
EP-3630291-B1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-01-10 — — EP claimed
US-20210147382-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2021-05-20 — — US claimed
EP-3630291-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 Cancer Research Technology Limited (GB) 2020-04-08 — — EP claimed
WO-2018215801-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2018-11-29 — — WO claimed
US-12110286-B2 Benzimidazolone derived inhibitors of BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-10-08 — — US disclosed
EP-3630291-B9 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-05-29 — — EP disclosed
EP-4374858-A2 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 Cancer Research Technology Limited (GB) 2024-05-29 — — EP disclosed
EP-3630291-B1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-01-10 — — EP disclosed
US-20210147382-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2021-05-20 — — US disclosed
US-20210147382-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2021-05-20 — — US disclosed
EP-3630291-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 Cancer Research Technology Limited (GB) 2020-04-08 — — EP disclosed
WO-2018215801-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2018-11-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147382-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 BCL6, BCL6B, BCL3 BCL6 1/4885
US-12110286-B2 Benzimidazolone derived inhibitors of BCL6 BCL6, BCL6B, BCL3 BCL6 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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