⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882325 | 0.81 | CNR2 (0.39) | — | |
| SCHEMBL24096652 | 0.79 | — | — | |
| SCHEMBL22224153 | 0.77 | — | — | |
| SCHEMBL25095295 | 0.76 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL5099353 | 0.71 | PPARA (0.38) | — | |
| SCHEMBL4853136 | 0.71 | PPARA (0.38) | — | |
| SCHEMBL2254668 | 0.71 | MEN1 (0.31) | — | |
| SCHEMBL2251477 | 0.71 | NOTUM (0.36) | — | |
| SCHEMBL3759539 | 0.71 | MEN1 (0.31) | — | |
| SCHEMBL13008101 | 0.70 | IDO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002279-A1 | NOVEL IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-01-06 | — | — | US | disclosed |
| US-20220002279-A1 | NOVEL IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-01-06 | — | — | US | disclosed |
| EP-3884940-A1 | NOVEL IMIDAZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
| EP-3884940-A1 | NOVEL IMIDAZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
| CN-112996505-A | Novel imidazole derivatives | 大正制药株式会社 | 2021-06-18 | — | — | CN | disclosed |
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |