Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ME2 | P23368 | 1/20 | 0.42 |
| ▸ | ME1 | P48163 | 1/20 | 0.42 |
| ▸ | ME3 | Q16798 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20639966 | 0.83 | AKR1C3 (0.58) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL2450111 | 0.83 | GFER (0.63) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL1576239 | 0.83 | MAPK1 (0.76) | AKR1C3MAPK1USP2POLBLMNA | |
| SCHEMBL23086761 | 0.81 | TRIM24 (0.54) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL23544891 | 0.80 | PANK3 (0.56) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL7380234 | 0.80 | MAPT (0.50) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL2555420 | 0.79 | AKR1C3 (0.65) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL16234824 | 0.78 | AKR1C3 (0.62) | AKR1C3MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL2452376 | 0.78 | GFER (0.56) | AKR1C3MAPK1CA12CA2CA9 | |
| SCHEMBL1576369 | 0.78 | MAPK1 (0.49) | AKR1C3MAPK1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |