Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893732 | 0.98 | METAP1 (0.43) | METAP1GABBR2GABBR1CYP1A2HPGD | |
| SCHEMBL18893731 | 0.96 | METAP1 (0.46) | METAP1GABBR2GABBR1CYP1A2HPGD | |
| SCHEMBL7921857 | 0.83 | METAP1 (0.52) | METAP1CYP1A2HPGDCA12CA1 | |
| SCHEMBL20575086 | 0.82 | CYP1A2 (0.52) | METAP1GABBR2GABBR1CYP1A2SIGMAR1 | |
| SCHEMBL19974194 | 0.81 | CYP1A2 (0.50) | METAP1GABBR2GABBR1CYP1A2S1PR1 | |
| SCHEMBL18893738 | 0.79 | CYP1A2 (0.53) | METAP1GABBR2GABBR1CYP1A2SIGMAR1 | |
| SCHEMBL28857191 | 0.78 | CYP1A2 (0.52) | METAP1GABBR2GABBR1CYP1A2SIGMAR1 | |
| SCHEMBL7805193 | 0.74 | METAP1 (0.57) | METAP1CYP1A2HPGDCA12CA1 | |
| SCHEMBL778183 | 0.73 | METAP1 (0.43) | METAP1CYP1A2HPGDCA12CA1 | |
| SCHEMBL20575014 | 0.72 | CYP1A2 (0.39) | METAP1CYP1A2HPGDMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180346739-A1 | POLYMERIC FLAME RETARDANT MIXTURES | CLARIANT PLASTICS & COATINGS LTD (CH) | 2018-12-06 | — | — | US | disclosed |