Cysteine

Cysteine

SCHEMBL20577013

C=CS(=O)(=O)C=C.NC(CS)C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.64
SLC7A11 Q9UPY5 1/20 0.64
GRIK1 P39086 6/20 0.40
GRIK2 Q13002 6/20 0.40
ENPEP Q07075 6/20 0.38
PMP22 Q01453 2/20 0.37
GRM1 Q13255 2/20 0.36
GRM2 Q14416 2/20 0.36
GSR P00390 2/20 0.34
CYP1A2 P05177 2/20 0.34
SLC7A5 Q01650 1/20 0.34
GRM8 O00222 1/20 0.34
GRM6 O15303 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRM5 P41594 1/20 0.34
GRIA1 P42261 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
SLC1A3 P43003 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cysteine SCHEMBL2778244 1.00 PTGS1 (0.64) PTGS1SLC7A11GRIK1GRIK2ENPEP
Serine SCHEMBL76998 0.82 SLC1A1 (0.42) PTGS1SLC7A11GRIK1GRIK2PMP22
Cysteine SCHEMBL28192928 0.81 PTGS1 (0.73) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL4023815 0.81 PTGS1 (0.73) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL4023819 0.81 PTGS1 (0.73) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL431234 0.81 PTGS1 (0.80) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL431233 0.81 PTGS1 (0.80) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL11127428 0.81 PTGS1 (0.80) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL11127430 0.81 PTGS1 (0.80) PTGS1SLC7A11GRIK1GRIK2ENPEP
Cysteine SCHEMBL1819440 0.80 PTGS1 (0.89) PTGS1SLC7A11GRIK1GRIK2ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200148804-A1 Novel Synthetic Polymers and Crosslinked Hydrogel Systems MCMASTER UNIVERSITY (CA) 2020-05-14 US claimed
EP-3630856-A1 NOVEL SYNTHETIC POLYMERS AND CROSSLINKED HYDROGEL SYSTEMS Mcmaster University (CA) 2020-04-08 EP claimed
WO-2018218346-A1 NOVEL SYNTHETIC POLYMERS AND CROSSLINKED HYDROGEL SYSTEMS MCMASTER UNIVERSITY (CA) 2018-12-06 WO claimed
US-20240150509-A1 Novel Synthetic Polymers and Crosslinked Hydrogel Systems MCMASTER UNIVERSITY (CA) 2024-05-09 US disclosed
US-11873358-B2 Synthetic polymers and crosslinked hydrogel systems MCMASTER UNIVERSITY (CA) 2024-01-16 US disclosed
US-20200148804-A1 Novel Synthetic Polymers and Crosslinked Hydrogel Systems MCMASTER UNIVERSITY (CA) 2020-05-14 US disclosed
EP-3630856-A1 NOVEL SYNTHETIC POLYMERS AND CROSSLINKED HYDROGEL SYSTEMS Mcmaster University (CA) 2020-04-08 EP disclosed
WO-2018218346-A1 NOVEL SYNTHETIC POLYMERS AND CROSSLINKED HYDROGEL SYSTEMS MCMASTER UNIVERSITY (CA) 2018-12-06 WO disclosed