Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | BRD4 | O60885 | 1/20 | 0.69 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306107 | 1.00 | DRD3 (0.73) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL25379465 | 0.99 | DRD3 (0.72) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL30306094 | 0.99 | DRD3 (0.72) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL25379277 | 0.94 | DRD3 (0.68) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL30306127 | 0.94 | DRD3 (0.68) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL25379605 | 0.94 | DRD3 (0.67) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL31679577 | 0.94 | DRD3 (0.67) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL26193832 | 0.93 | DRD3 (0.72) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL25380525 | 0.93 | DRD3 (0.71) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL30306102 | 0.93 | DRD3 (0.71) | DRD3KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630779-B1 | ANTIBIOTIC RESISTANCE BREAKERS | KING S COLLEGE LONDON (GB) | 2025-09-03 | — | — | EP | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| CN-110869373-B | Antibiotic resistance disruptors | 伦敦皇家学院 | 2023-03-07 | — | — | CN | disclosed |
| EP-3630779-A1 | ANTIBIOTIC RESISTANCE BREAKERS | Kings College London (GB) | 2020-04-08 | — | — | EP | disclosed |
| CN-110869373-A | Antibiotic resistance disruptors | 伦敦皇家学院 | 2020-03-06 | — | — | CN | disclosed |
| WO-2018220365-A1 | ANTIBIOTIC RESISTANCE BREAKERS | KING'S COLLEGE LONDON (GB) | 2018-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746116-B2 | Antibiotic resistance breakers | ABCC1, ARL1, AKR1C3 | DRD3 594/4885KDM4E 3599/4885ALDH1A1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.