SCHEMBL2057767

SCHEMBL2057767

[2H]C([2H])(Br)C#CCC#CCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2057684 0.91
SCHEMBL2057167 0.83
SCHEMBL8580513 0.78
SCHEMBL16232226 0.77
SCHEMBL14964623 0.77
SCHEMBL3459658 0.77
SCHEMBL12621545 0.77
SCHEMBL1807609 0.72
SCHEMBL12621538 0.72 KDM4E (0.30)
SCHEMBL20767781 0.69 RECQL (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325512-A1 Neurodegenerative Disorders And Muscle Diseases Implicating Pufas BIOJIVA LLC (US) 2025-10-23 US disclosed
US-20220378734-A1 NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS RTMFP ENTERPRISES INC. 2022-12-01 US disclosed
US-11510888-B2 Alleviating oxidative stress disorders with PUFA derivatives RETROTOPE, INC. (US) 2022-11-29 US disclosed
US-RE49238-E1 Alleviating oxidative stress disorders with PUFA derivatives RETROTOPE, INC. (US) 2022-10-11 US disclosed
US-20220304968-A1 OXIDATIVE RETINAL DISEASES BIOJIVA LLC 2022-09-29 US disclosed
US-11285125-B2 Oxidative retinal diseases RETROTOPE, INC. (US) 2022-03-29 US disclosed
US-11241409-B2 Neurodegenerative disorders and muscle diseases implicating PUFAs RETROTOPE, INC. (US) 2022-02-08 US disclosed
EP-2701698-B1 DISORDERS IMPLICATING PUFA OXIDATION RETROTOPE INC (US) 2020-12-23 EP disclosed
EP-3730135-A1 IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY Retrotope, Inc. (US) 2020-10-28 EP disclosed
EP-3689342-A1 OXIDATIVE RETINAL DISEASES Retrotope, Inc. (US) 2020-08-05 EP disclosed
US-10052299-B2 Alleviating oxidative stress disorders with PUFA derivatives RETROTOPE, INC. (US) 2018-08-21 US disclosed
US-20140147428-A1 NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS RETROTOPE, INC. (US) 2014-05-29 US disclosed
US-20140050712-A1 DISORDERS IMPLICATING PUFA OXIDATION RETROTOPE, INC. (US) 2014-02-20 US disclosed
US-20140050712-A1 DISORDERS IMPLICATING PUFA OXIDATION RETROTOPE, INC. (US) 2014-02-20 US disclosed
US-20140044692-A1 IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY RETROTOPE, INC. (US) 2014-02-13 US disclosed
US-20140044693-A1 OXIDATIVE RETINAL DISEASES RETROTOPE, INC. (US) 2014-02-13 US disclosed
US-20140044693-A1 OXIDATIVE RETINAL DISEASES RETROTOPE, INC. (US) 2014-02-13 US disclosed
US-20140044692-A1 IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY RETROTOPE, INC. (US) 2014-02-13 US disclosed
US-20110105609-A1 ALLEVIATING OXIDATIVE STRESS DISORDERS WITH PUFA DERIVATIVES RETROTOPE, INC. (US) 2011-05-05 US disclosed
US-20110105609-A1 ALLEVIATING OXIDATIVE STRESS DISORDERS WITH PUFA DERIVATIVES RETROTOPE, INC. (US) 2011-05-05 US disclosed