Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577872 | 0.88 | KDR (0.57) | KDRBRAF | |
| SCHEMBL20577758 | 0.87 | KDR (0.60) | KDRBRAF | |
| SCHEMBL28679600 | 0.85 | KDR (0.62) | KDRBRAF | |
| SCHEMBL20577720 | 0.85 | KDR (0.70) | KDRBRAF | |
| SCHEMBL20577859 | 0.84 | KDR (0.65) | KDRBRAF | |
| SCHEMBL20577809 | 0.84 | KDR (0.63) | KDRBRAF | |
| SCHEMBL20578165 | 0.84 | KDR (0.63) | KDRBRAF | |
| SCHEMBL20577909 | 0.81 | KDR (0.63) | KDRBRAF | |
| SCHEMBL19233425 | 0.81 | KDR (0.81) | KDRBRAF | |
| SCHEMBL29448689 | 0.80 | KDR (0.77) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071543-B | Pyridine derivatives inhibiting RAF kinase and vascular endothelial growth factor receptor, process for their preparation, pharmaceutical compositions containing them and their use | 三进制药株式会社 | 2021-07-16 | — | — | CN | disclosed |
| EP-3412670-A1 | PYRIDINE DERIVATIVE INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2018-12-12 | — | — | EP | disclosed |