Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410871 | 1.00 | BTK (1.00) | BTK | |
| SCHEMBL29410864 | 0.91 | BTK (0.84) | BTK | |
| SCHEMBL20578191 | 0.91 | BTK (0.84) | BTK | |
| SCHEMBL20716520 | 0.90 | BTK (1.00) | BTK | |
| SCHEMBL20716231 | 0.90 | BTK (1.00) | BTK | |
| SCHEMBL20578278 | 0.89 | BTK (0.80) | BTK | |
| SCHEMBL19230306 | 0.88 | BTK (0.79) | BTK | |
| SCHEMBL20716471 | 0.88 | BTK (1.00) | BTK | |
| SCHEMBL20716232 | 0.88 | BTK (1.00) | BTK | |
| SCHEMBL29410874 | 0.88 | BTK (1.00) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033069-B | Novel irreversible Bruton's tyrosine kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-03-04 | — | — | CN | disclosed |
| EP-3412657-B1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | HEFEI INST PHYSICAL SCI CAS (CN) | 2021-11-24 | — | — | EP | disclosed |
| US-10669238-B2 | Irreversible bruton's tyrosine kinase inhibitor | HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2020-06-02 | — | — | US | disclosed |
| US-10669238-B2 | Irreversible bruton's tyrosine kinase inhibitor | HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2020-06-02 | — | — | US | disclosed |
| US-20190040013-A1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2019-02-07 | — | — | US | disclosed |
| US-20190040013-A1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2019-02-07 | — | — | US | disclosed |
| EP-3412657-A1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | Hefei Institutes of Physical Sicence, Chinese Academy of Sciences (CN) | 2018-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669238-B2 | Irreversible bruton's tyrosine kinase inhibitor | BTK, ABL1, SYK | BTK 1/4885 |
| US-20190040013-A1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | BTK, ABL1, SYK | BTK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.