⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058354 | 1.00 | — | — | |
| SCHEMBL2058295 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8961364 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL8961366 | 0.98 | — | — | |
| SCHEMBL6048247 | 0.93 | — | — | |
| Homoserine Lactone SCHEMBL79969 | 0.84 | — | — | |
| Homoserine Lactone SCHEMBL79466 | 0.84 | — | — | |
| Homoserine Lactone SCHEMBL79968 | 0.84 | — | — | |
| SCHEMBL731550 | 0.84 | TSHR (0.32) | — | |
| Homoserine Lactone SCHEMBL7217249 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258320-B2 | N alkylcarbonyl amino lactone compounds and their use | WEI EDWARD TAK (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120184608-A1 | N alkylcarbonyl amino lactone compounds and their use | WEI EDWARD TAK (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110160303-A1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | EDWARD TAK WEI | 2011-06-30 | — | — | US | disclosed |
| EP-2161252-A1 | N-Alkylcarbonyl-amino acid ester and N-Alkylcarbonyl-amino lactone compounds and their use | Wei, Edward T. (US) | 2010-03-10 | — | — | EP | disclosed |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | WEI EDWARD TAK | 2008-09-18 | — | — | US | disclosed |