Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 1.00 |
| ▸ | MAOB | P27338 | 10/20 | 1.00 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | HTR1B | P28222 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14881820 | 1.00 | KDM1A (1.00) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL14881821 | 1.00 | KDM1A (1.00) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL16394490 | 1.00 | KDM1A (1.00) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL22181476 | 0.90 | KDM1A (0.85) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL14880891 | 0.87 | KDM1A (1.00) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL14880807 | 0.87 | KDM1A (1.00) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL14880736 | 0.87 | KDM1A (1.00) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL29721107 | 0.85 | KDM1A (0.74) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL16407927 | 0.82 | KDM1A (0.85) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL14880462 | 0.82 | KDM1A (0.85) | KDM1AMAOBCISD1SLC6A2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329256-B2 | (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors | ORYZON GENOMICS, S.A. (ES) | 2019-06-25 | — | — | US | disclosed |
| US-20180354902-A1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2018-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354902-A1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | KDM1B, KDM1A, KDM2A | KDM1A 2/4885MAOB 165/4885CISD1 904/4885 |
| US-10329256-B2 | (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors | KDM1B, KDM1A, KDM2A | KDM1A 2/4885MAOB 165/4885CISD1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.