Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 14/20 | 0.60 |
| ▸ | FLT3 | P36888 | 14/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.60 |
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917459 | 0.89 | KDR (0.62) | KITFLT3SRCKDR | |
| SCHEMBL29539891 | 0.89 | KDR (0.62) | KITFLT3SRCKDR | |
| SCHEMBL5889064 | 0.87 | KIT (0.62) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL12078234 | 0.86 | KDR (0.47) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL29539419 | 0.80 | KIT (0.57) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL22917465 | 0.80 | KIT (0.57) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL20633811 | 0.80 | CHRNA7 (0.46) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL20633281 | 0.80 | CHRNA7 (0.51) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL22917493 | 0.79 | KIT (0.80) | KITFLT3NTRK1SRCKDR | |
| SCHEMBL24292329 | 0.77 | FLT3 (0.75) | KITFLT3NTRK1SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831596-B | Aminothiazole compounds as protein kinase inhibitors | 台湾卫生研究院 | 2025-01-24 | — | — | CN | disclosed |
| EP-3638237-B1 | AMINOTHIAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | NATIONAL HEALTH RES INST (TW) | 2023-04-19 | — | — | EP | disclosed |
| US-20220288069-A1 | INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. | 2022-09-15 | — | — | US | disclosed |
| EP-3999064-A1 | INHIBITORS OF TYROSINE KINASE | Bridgene Biosciences, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114401722-A | Inhibitors of tyrosine kinases | 布里奇恩生物科学公司 | 2022-04-26 | — | — | CN | disclosed |
| US-11299489-B1 | Thiazole compounds as protein kinase inhibitors | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-04-12 | — | — | US | disclosed |
| WO-2021016102-A1 | INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2021-01-28 | — | — | WO | disclosed |
| EP-3638237-A1 | AMINOTHIAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | Shih, Chuan (US) | 2020-04-22 | — | — | EP | disclosed |
| CN-110831596-A | Aminothiazole compounds as protein kinase inhibitors | 财团法人卫生研究院 | 2020-02-21 | — | — | CN | disclosed |
| US-10300061-B2 | Aminothiazole compounds as protein kinase inhibitors | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2019-05-28 | — | — | US | disclosed |
| US-10300061-B2 | Aminothiazole compounds as protein kinase inhibitors | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2019-05-28 | — | — | US | disclosed |
| WO-2018231910-A1 | AMINOTHIAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2018-12-20 | — | — | WO | disclosed |
| US-20180353509-A1 | AMINOTHIAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | NATIONAL HEALTH RES INST (TW) | 2018-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220288069-A1 | INHIBITORS OF TYROSINE KINASE | ABL1, SRC, LCK | KIT 688/4885FLT3 41/4885NTRK1 459/4885 |
| US-20180353509-A1 | AMINOTHIAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | ABL1, ERBB2, CSNK1E | KIT 611/4885FLT3 207/4885NTRK1 784/4885 |
| US-11299489-B1 | Thiazole compounds as protein kinase inhibitors | ABL1, RET, ERBB2 | KIT 994/4885FLT3 94/4885NTRK1 760/4885 |
| US-10300061-B2 | Aminothiazole compounds as protein kinase inhibitors | ABL1, ERBB2, CSNK1E | KIT 611/4885FLT3 207/4885NTRK1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.