Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20584877 | 1.00 | CHRM4 (0.49) | CHRM4CHRM2ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL20584873 | 1.00 | CHRM4 (0.49) | CHRM4CHRM2ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL15619002 | 0.84 | CHRM4 (0.49) | CHRM4CHRM2ALDH1A1CHRM1GAA | |
| SCHEMBL20585988 | 0.84 | CHRM4 (0.47) | CHRM4CHRM2ALDH1A1CHRM1GAA | |
| SCHEMBL20585987 | 0.84 | CHRM4 (0.47) | CHRM4CHRM2ALDH1A1CHRM1GAA | |
| SCHEMBL20585989 | 0.84 | CHRM4 (0.47) | CHRM4CHRM2ALDH1A1CHRM1GAA | |
| SCHEMBL20585768 | 0.82 | CHRM4 (0.55) | CHRM4CHRM2ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL20585763 | 0.82 | CHRM4 (0.55) | CHRM4CHRM2ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL20585742 | 0.82 | CHRM4 (0.57) | CHRM4CHRM2ALDH1A1CHRM1GAA | |
| SCHEMBL20585745 | 0.82 | CHRM4 (0.57) | CHRM4CHRM2ALDH1A1CHRM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638658-B1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2025-10-08 | — | — | EP | claimed |
| US-11352342-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-07 | — | — | US | claimed |
| US-20210040067-A1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2021-02-11 | — | — | US | claimed |
| US-10752610-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-08-25 | — | — | US | claimed |
| EP-3638658-A1 | PHARMACEUTICAL COMPOUNDS | Heptares Therapeutics Limited (GB) | 2020-04-22 | — | — | EP | claimed |
| US-20190276437-A1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2019-09-12 | — | — | US | claimed |
| US-10329278-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-06-25 | — | — | US | claimed |
| US-20180362507-A1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2018-12-20 | — | — | US | claimed |
| WO-2018229511-A1 | PHARMACEUTICAL COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2018-12-20 | — | — | WO | claimed |
| EP-3638658-B1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2025-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040067-A1 | PHARMACEUTICAL COMPOUNDS | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885ALDH1A1 1597/4885 |
| US-11352342-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885ALDH1A1 1597/4885 |
| US-10329278-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885ALDH1A1 2039/4885 |
| US-20190276437-A1 | PHARMACEUTICAL COMPOUNDS | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885ALDH1A1 1597/4885 |
| US-20180362507-A1 | PHARMACEUTICAL COMPOUNDS | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885ALDH1A1 2039/4885 |
| US-10752610-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885ALDH1A1 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.