SCHEMBL205857

SCHEMBL205857

COc1nc(N)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.58
NT5E P21589 1/20 0.56
P2RY6 Q15077 2/20 0.53
P2RY2 P41231 1/20 0.53
P2RY4 P51582 1/20 0.53
ENPP1 P22413 5/20 0.51
P2RY1 P47900 3/20 0.51
P2RX1 P51575 2/20 0.51
P2RX3 P56373 2/20 0.51
P2RY11 Q96G91 1/20 0.51
P2RX4 Q99571 1/20 0.51
P2RY12 Q9H244 1/20 0.49
DTYMK P23919 4/20 0.49
RNASEL Q05823 1/20 0.48
P2RX2 Q9UBL9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30848914 1.00 POLB (0.58) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL30279681 0.92 NT5E (0.60) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL12932286 0.89 NT5E (0.67) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL345288 0.89 NT5E (0.67) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL4820794 0.89 NT5E (0.67) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL17117823 0.89 NT5E (0.67) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL29400356 0.89 NT5E (0.67) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL8079921 0.87 POLB (0.56) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL12729466 0.87 POLB (0.52) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL17833848 0.87 POLB (0.52) POLBNT5EP2RY6P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140170689-A1 Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-06-19 US claimed
US-10662485-B2 Bioagent detection oligonucleotides IBIS BIOSCIENCES, INC. (US) 2020-05-26 US disclosed
US-9970061-B2 Bioagent detection oligonucleotides IBIS BIOSCIENCES, INC. (US) 2018-05-15 US disclosed
US-9758840-B2 Parasite detection via endosymbiont detection IBIS BIOSCIENCES, INC. (US) 2017-09-12 US disclosed
US-9719083-B2 Bioagent detection methods IBIS BIOSCIENCES, INC. (US) 2017-08-01 US disclosed
US-20160325283-A1 BIOAGENT DETECTION SYSTEMS, DEVICES, AND METHODS IBIS BIOSCIENCES INC (US) 2016-11-10 US disclosed
US-9447462-B2 Methods for concurrent identification and quantification of an unknown bioagent IBIS BIOSCIENCES, INC. (US) 2016-09-20 US disclosed
EP-2462244-B1 NON-MASS DETERMINED BASE COMPOSITIONS FOR NUCLEIC ACID DETECTION IBIS BIOSCIENCES INC (US) 2016-07-20 EP disclosed
US-9393564-B2 Bioagent detection systems, devices, and methods IBIS BIOSCIENCES, INC. (US) 2016-07-19 US disclosed
US-20160108461-A1 TARGETED WHOLE GENOME AMPLIFICATION METHOD FOR IDENTIFICATION OF PATHOGENS IBIS BIOSCIENCES, INC. 2016-04-21 US disclosed
US-20060259249-A1 Rapid identification of microbial agents IBIS BIOSCIENCES, INC. 2006-11-16 US disclosed
US-20060205040-A1 Compositions for use in identification of adventitious viruses IBIS BIOSCIENCES, INC. 2006-09-14 US disclosed
WO-2006094238-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF ADVENTITIOUS VIRUSES ISIS PHARMACEUTICALS, INC. (US) 2006-09-08 WO disclosed
WO-2006071241-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA ISIS PHARMACEUTICALS, INC. (US) 2006-07-06 WO disclosed
US-20060057605-A1 Compositions for use in identification of viral hemorrhagic fever viruses ISIS PHARMACEUTICALS, INC. (US) 2006-03-16 US disclosed
WO-2005098047-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA ISIS PHARMACEUTICALS, INC. (US) 2005-10-20 WO disclosed
WO-2005094421-A2 METHODS FOR CONCURRENT IDENTIFICATION AND QUANTIFICATION OF AN UNKNOWN BIOAGENT ISIS PHARMACEUTICALS, INC. (US) 2005-10-13 WO disclosed
WO-2005091971-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF ALPHAVIRUSES ISIS PHARMACEUTICALS, INC. (US) 2005-10-06 WO disclosed
WO-2005092059-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF VIRAL HEMORRHAGIC FEVER VIRUSES ISIS PHARMACEUTICALS, INC. (US) 2005-10-06 WO disclosed
WO-2005089128-A2 RAPID IDENTIFICATION OF MICROBIAL AGENTS ISIS PHARMACEUTICALS, INC. (US) 2005-09-29 WO disclosed