Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910000 | 1.00 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL8909987 | 1.00 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL7347831 | 1.00 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL22305235 | 1.00 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL31506428 | 1.00 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL5541452 | 1.00 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| Oxalic Acid SCHEMBL7207478 | 0.98 | ATM (0.59) | ATMCTSSCTSKCTSLCTSB | |
| Oxalic Acid SCHEMBL8716603 | 0.98 | ATM (0.59) | ATMCTSSCTSKCTSLCTSB | |
| Malonic Acid SCHEMBL8710814 | 0.96 | ATM (0.58) | ATMCTSSCTSKCTSLCTSB | |
| Oxalic Acid SCHEMBL7211894 | 0.96 | ATM (0.58) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454168-B | Synthesis method of ritonavir intermediate BDH | 南通森萱药业有限公司 | 2022-04-05 | — | — | CN | claimed |
| EP-1302468-A1 | Processes and intermediates for manufacturing retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2003-04-16 | — | — | EP | claimed |
| EP-1090914-A2 | Processes and intermediates for manufacturing retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | claimed |
| EP-0724563-B1 | Intermediates for the preparation of a substituted 2,5-diamino-3-hydroxyhexane. | ABBOTT LAB (US) | 1999-09-01 | — | — | EP | claimed |
| US-5892052-A | Process for making retroviral protease inhibiting compounds | ABBOTT LABORTORIES (US) | 1999-04-06 | — | — | US | claimed |
| US-5837873-A | PROTECTED OXYDIAMINES | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | claimed |
| US-5786500-A | Process for the preparation of a substituted 2.5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1998-07-28 | — | — | US | claimed |
| US-5654466-A | Process for the preparation of a disubstituted 2,5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1997-08-05 | — | — | US | claimed |
| EP-0727419-A2 | Retroviral protease inhibiting compounds | Abbott Laboratories (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0724563-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LABORATORIES (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011224-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LABORATORIES (US) | 1995-04-27 | — | — | WO | claimed |
| CN-222983869-U | Filtering device for ritonavir intermediate BDH production | 南通森萱药业有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-219647488-U | Reaction kettle for ritonavir intermediate BDH (BDH) Grignard reaction | 南通森萱药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-115368498-A | Preparation method and application of eutectic solvent type molecularly imprinted polymer based on magnetic metal organic framework material carrier | 河南师范大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-111454168-B | Synthesis method of ritonavir intermediate BDH | 南通森萱药业有限公司 | 2022-04-05 | — | — | CN | disclosed |
| US-5484801-A | Pharmaceutical composition for inhibiting HIV protease | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1995011224-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LABORATORIES (US) | 1995-04-27 | — | — | WO | disclosed |
| WO-1995007696-A1 | PHARMACEUTICAL COMPOSITION OF HIV-PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1995-03-23 | — | — | WO | disclosed |
| US-5354866-A | Treating HIV infections | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0486948-A2 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1992-05-27 | — | — | EP | disclosed |