Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599779 | 0.90 | MEN1 (0.39) | MEN1KMT2AKDM4EGAAJAK2 | |
| SCHEMBL20600333 | 0.85 | ERCC5 (0.35) | MEN1KMT2AKDM4EMAPTDHODH | |
| SCHEMBL20621792 | 0.83 | CYP3A4 (0.50) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL29965238 | 0.83 | CYP3A4 (0.50) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL20600156 | 0.78 | RXFP1 (0.41) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL20621881 | 0.74 | CYP3A4 (0.50) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL20600158 | 0.71 | CCNC (0.40) | KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20599776 | 0.69 | GSK3B (0.39) | MEN1KMT2AMAPTLMNAROCK2 | |
| SCHEMBL20622111 | 0.68 | CYP3A4 (0.52) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL28371995 | 0.66 | MEN1 (0.34) | MEN1KMT2AKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615527-B1 | NEW AZAQUINOLINE DERIVATIVES | ELANCO ANIMAL HEALTH GMBH (DE) | 2024-03-06 | — | — | EP | disclosed |
| US-11485733-B2 | Azaquinoline derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2022-11-01 | — | — | US | disclosed |
| US-20200131175-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
| EP-3615527-A1 | NEW AZAQUINOLINE DERIVATIVES | Bayer Animal Health GmbH (DE) | 2020-03-04 | — | — | EP | disclosed |
| WO-2019002132-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131175-A1 | NEW AZAQUINOLINE DERIVATIVES | RECQL, H1-5, CHRM1 | MEN1 431/4885KMT2A 253/4885KDM4E 1513/4885 |
| US-11485733-B2 | Azaquinoline derivatives | RECQL, H1-5, H1-3 | MEN1 175/4885KMT2A 309/4885KDM4E 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.